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Author: s | 2025-04-24

TGF is a Member at Bukkit Forums. Log in or Sign up. Bukkit Forums. Home Members TGF Last Activity: Joined: Messages: 113 Likes

TGF haiku - The Gear Forum

Might want to use Anaconda to decompile those if they're Games Factory 2 / MMF2 era games. #9 Hope this ain't too much of a necropost (last post was January of this year at least), but what happens/does it mean if the Clickteam file gets a "stop status encountered" error when trying to extract? #10 Hope this ain't too much of a necropost (last post was January of this year at least), but what happens/does it mean if the Clickteam file gets a "stop status encountered" error when trying to extract? Doesn't sound good though, maybe the .MFA file is incompatible with that version? #11 Aha, Beavis & Butthead, another man of culture! ;)It is quite a sporadic error, as there's no pattern as to which .cca/TGF .gams it seems to pop up on, out of the files I've tried the Extractor on. #12 Aha, Beavis & Butthead, another man of culture! ;)It is quite a sporadic error, as there's no pattern as to which .cca/TGF .gams it seems to pop up on, out of the files I've tried the Extractor on. that's what I'm gonna guess then, I don't think anaconda can decomp the absolute latest stuff afaik?

A TGF livestream? - The Gear Forum

Expression of ACVRL1 in the cytoplasm of CRC cells. Furthermore, our study revealed the biological function of ACVRL1 independent of the TGF-β pathway and angiogenesis. We found ACVRL1 promotes mTKI resistance independently by stabilizing GPX2, rather than through the classical TGF-β signalling pathway. ACVRL1 stabilizes GPX2 through USP15-mediated deubiquitination. The ROS-scavenging enzyme GPX2 is a critical determinant of tumour differentiation, growth, and metastasis in CRC. GPX2 maintains low intracellular ROS level, thereby maintaining the clonogenic and metastatic tumour cell populations in CRC [14]. Elevated GPX2 mediates the resistance of lung adenocarcinoma to cisplatin [27]. However, whether GPX2 is involved in drug resistance in CRC is still unclear. ROS are inevitable products of cellular metabolism in aerobic life and are closely related to drug resistance in tumours [28]. Our study reveals that upregulated ACVRL1 neutralizes ROS by stabilizing GPX2, leading to the intracellular ‘redox reset’, which contributes to the general resistance of CRC to mTKIs.The Wnt/β-catenin signalling pathway is an evolutionarily conserved and unique signalling pathway that regulates cell proliferation, differentiation, invasion and metastasis during the initiation and progression of CRC [29]. Up to 80% of CRCs carries APC mutation, as a result, β-catenin accumulates, translocates to the nucleus, and associates with TCF/LEF, leading to subsequent transcriptional activation of genes associated with CRC development [30, 31]. Our study indicates that the low ORRs of mTKIs may partly due to the upregulated ACVRL1 which is activated by the general activation of the Wnt/β-catenin pathway in CRC. We further found that the TCF/LEF family are not potential transcription factors of ACVRL1 through the prediction of Transcription factor databases, so we hypothesized that β-catenin might regulate ACVRL1 at the post-transcriptional level. We next found that β-catenin could promote lncRNA-KCNQ1OT1 transcription through direct binding to the KCNQ1OT1 promoter. Dual luciferase reporter assay confirmed that miR-7-5p

TGF K98's - Gunboards Forums

Transl Med 14(1):86. Article PubMed PubMed Central Google Scholar Le Grand B, Letienne R, Dupont-Passelaigue E, Lantoine-Adam F, Longo F, David-Dufilho M, Michael G, Nishida K, Catheline D, Legrand P, Hatem S, Nattel S (2014) F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy. Naunyn Schmiedeberg's Arch Pharmacol 387(7):667–677. Article Google Scholar Lee KW, Everett TH 4th, Rahmutula D et al (2006) Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure. Circulation 114(16):1703–1712. Article CAS PubMed PubMed Central Google Scholar Fu H, Li G, Liu C, Li J, Wang X, Cheng L, Liu T (2015) Probucol prevents atrial remodeling by inhibiting oxidative stress and TNF-α/NF-κB/TGF-β signal transduction pathway in alloxan-induced diabetic rabbits. J Cardiovasc Electrophysiol 26(2):211–222. Article PubMed Google Scholar Rahmutula D, Marcus GM, Wilson EE, Ding CH, Xiao Y, Paquet AC, Barbeau R, Barczak AJ, Erle DJ, Olgin JE (2013) Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1. Cardiovasc Res 99(4):769–779. Article CAS PubMed PubMed Central Google Scholar Naser AR, Sankaranarayanan K, Kensuke T et al (2013) Disruption of Nrf2 promotes atrial remodeling and fibrillation on aging. Circ Res 113:A284 Google Scholar Rucker-Martin C, Milliez P, Tan S, Decrouy X, Recouvreur M, Vranckx R, Delcayre C, Renaud JF, Dunia I, Segretain D, Hatem SN (2006) Chronic hemodynamic overload of the atria is an important factor for gap junction remodeling in human and rat hearts. Cardiovasc Res 72(1):69–79. Article CAS PubMed Google Scholar Woods CE, Olgin J (2014) Atrial fibrillation therapy now and in the future: drugs, biologicals, and ablation. Circ Res 114(9):1532–1546. Article CAS PubMed PubMed Central Google Scholar Xue LX, Zhang T, Zhao YW, Geng Z, Chen JJ, Chen H (2016) Efficacy and safety comparison of DL-3-n-butylphthalide and Cerebrolysin:. TGF is a Member at Bukkit Forums. Log in or Sign up. Bukkit Forums. Home Members TGF Last Activity: Joined: Messages: 113 Likes Toronto Global Forum. The Toronto Global Forum (TGF) was launched in 2025 and is hosted by the IEFA in association with Integra Capital. The TGF gathers international thought leaders

TEENAGE GIRLS FORUM (TGF) - Facebook

Added ability to upload tracks into the Active Log OR saved tracks (Garmin feature only) Added different Lat/Lon display and entering types (degrees, min, secs) Made waypoint dialog remember and set the file a waypoint was last added to (for adding waypoints in succession) Added Speed scaling option to profile (colored based on speed) Added Export to SVG (Scalable Vector Graphics) format Added Import of Maptech MXF (waypoint) files Fixed average speed computation, tuned ascent/descent totals, added current speed to profile statistic displays Fixed bug saving out "cut" tracks Fixed bug with elevation shading after downloading a new track Fixed bug loading new files while GPS xfer is in progress Fixed bug with creating networks without elevation data Eliminated need for binary (.tgf) network files (simulation now runs on .gpx files)1.25 - [11/15/02] Fixed floating point exception handling (prevented startup on some CPUs) Fixed crashing issues with clipping on lower end graphics cards (4MB) Fixed GPX string reading w/o CDATA Eliminated `Way Out 128M' from tile set choices Better GPS interface errors, robust detection of COM port errors Fixed live tracking bug with Lat/Lon display Further development of Trail Simulator1.2 - [11/03/02] Added Magellan GPSR support Added Basic Trail Simulation (beta feature only) Number of internet download threads is now configurable Proxy Server support added Downloading tracks are now shown as the transfer proceeds Added smooth zooming feature Fixed bug where waypoint comments were not being downloaded correctly PGUP/PGDOWN now do zoom in/out (for laptop use) Various speed ups to

Year Anniversary for TGF? - The Gear Forum

Genes promoter in bovine Cloned embryo development. Dissertation, Huazhong Agricultural UniversityShi Y, Hu B, Wang Z, Wu X, Luo L, Li S, Wang S, Zhang K, Wang H (2023) Functional role of GATA3 and CDX2 in lineage specification during bovine early embryonic development. Reproduction 165(3):325–333. PubMed PubMed Central CAS Google Scholar Shin M, Alev C, Wu Y, Nagai H, Sheng G (2011) Activin/TGF-beta signaling regulates Nanog expression in the epiblast during gastrulation. Mech Develop 128(5–6):268–278. CAS Google Scholar Silva J, Chambers I, Pollard S, Smith A (2006) Nanog promotes transfer of pluripotency after cell fusion. Nature 441(7096):997–1001. PubMed CAS Google Scholar Stöger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H (1993) Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Trends Genet 9(7):234. Google Scholar Sun Y, Liu J, Wang B, Liu X, Du X, Liu Y, Zhang Q (2019) Klf4 could be activated by Pou5f3/Stat3 to induce the expression of Nanog in Japanese flounder. Gene 687:56–63. PubMed CAS Google Scholar Suzuki A, Raya A, Kawakami Y, Morita M, Matsui T, Nakashima K, Gage F, Rodriguez-Esteban C, Izpisua Belmonte J (2006) Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. P Natl Acad Sci USA 103(27):10294–10299. CAS Google Scholar Tian J, Chng SC, Ong JX, Reversade B (2011) Cloning and functional study of Nanog in zebrafish. Dev Biol 356(1):234. Google Scholar Tzung KW, Goto R, Saju JM, Sreenivasan R, Saito T, Arai K, Yamaha E, Hossain MS, Calvert MEK, Orbán L (2015) Early depletion of primordial germ cells in zebrafish promotes testis formation. Stem Cell Rep 4(1):61–73. CAS Google Scholar Veil M, Schaechtle M, Gao M, Kirner V, Buryanova L, Grethen R, Onichtchouk D (2018) Maternal Nanog is required for zebrafish embryo architecture and

TGF YouTube channel? - The Gear Forum

Central Google Scholar Bikou O, Thomas D, Trappe K, Lugenbiel P, Kelemen K, Koch M et al (2011) Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model. Cardiovasc Res 92(2):218–225. Article CAS PubMed Google Scholar Cai WX, Zhang J, Hu DH (2009) Defensive pathway of Nrf2/ARE involved in oxidative and chemical stress. Chin J Biochem Mol Biol 25(04):297–303CAS Google Scholar Cardin S, Libby E, Pelletier P, le Bouter S, Shiroshita-Takeshita A, le Meur N, Leger J, Demolombe S, Ponton A, Glass L, Nattel S (2007) Contrasting gene expression profiles in two canine models of atrial fibrillation. Circ Res 100(3):425–433. Article CAS PubMed Google Scholar Cerebrovascular Disease Working Groups, Chinese Academy of Neurology (2010) Guidelines for the management of iscemic stroke (China 2010). Chin J Neurol (Chin) 43:146–153 Google Scholar Choi EK, Chang PC, Lee YS, Lin SF, Zhu W, Maruyama M, Fishbein MC, Chen Z, Rubart-von der Lohe M, Field LJ, Chen PS (2012) Triggered firing and atrial fibrillation in transgenic mice with selective atrial fibrosis induced by overexpression of TGF-β1. Circ J 76(6):1354–1362. Article CAS PubMed PubMed Central Google Scholar Chong E, Chang SL, Hsiao YW, Singhal R, Liu SH, Leha T, Lin WY, Hsu CP, Chen YC, Chen YJ, Wu TJ, Higa S, Chen SA (2015) Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation. Heart Rhythm 12(5):1046–1056. Article PubMed Google Scholar Cui LY, Zhu YC, Gao S, Wang JM, Peng B, Ni J, Zhou LX, He J, Ma XQ (2013) Ninety-day administration of dl-3-n-butylphthalide for acute ischemic stroke: a randomized, double-blind trial. Chin Med J 126(18):3405–3410CAS PubMed Google Scholar European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery, ..., ESC Committee for Practice Guidelines (2010) Guidelines for the management of atrial fibrillation: the Task Force

TGF Speakers - Think Global Forum

As a result, the increased ROS clearance and decreased cell apoptosis eventually lead to mTKI resistance in CRC.ConclusionsOur results demonstrate that the Wnt/β-catenin/KCNQ1OT1/miR-7-5p/ACVRL1/GPX2 biological axis plays a vital role in CRC, targeting which may be an effective approach for overcoming mTKI resistance. Peer Review reports BackgroundColorectal cancer (CRC) is the third most common type of cancer [1]. However, as the disease progresses, approximately 50% of CRC patients will eventually develop metastatic CRC (mCRC), which has a 5-year survival rate of less than 20% [2, 3]. Owing to the broad anti-tumour spectrum, multitarget tyrosine kinase inhibitors (mTKIs), such as Regorafenib and Sorafenib, are considered as potential target drugs for various solid tumours [4]. However, the clinical performance of mTKIs in CRC is suboptimal. In the phase III CORRECT trial, Regorafenib improved the overall survival of patients by 1.4 months and the objective response rate (ORR) of Regorafenib was only 1.0% [5]. Several phase I/II clinical studies have observed that a small number of CRC patients treated with Sorafenib had stable disease, but no objective response was obtained [6]. The overall clinical response of mTKIs in CRC is limited, and the underlying mechanism of this poor response still needs to be further explored.ACVRL1 is a type I receptor for TGF-β family ligands BMP9 and BMP10 and important regulator of normal blood vessel development [7]. Owing to its critical role in angiogenesis, ACVRL1 has gained attention as a therapeutic target in cancer. Pharmacological targeting ACVRL1 by using anti-ACVRL1 antibody or a ligand-trapping agent can inhibit tumour growth and metastasis in preclinical models [8,9,10]. Despite the increased knowledge about the role of ACVRL1 in endothelial cell biology and angiogenesis, few studies have reported the role and therapeutic value of ACVRL1 in CRC cells. Furthermore, the downstream effectors of ACVRL1 remain largely elusive, the roles. TGF is a Member at Bukkit Forums. Log in or Sign up. Bukkit Forums. Home Members TGF Last Activity: Joined: Messages: 113 Likes

Gastroscopes Olympus TGF-UC180J Forums

Zhang L, Watson KD, Mancuso P, Lappin P, et al. Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies. Cancer Res. 2011;71:1362–73.Article CAS PubMed PubMed Central Google Scholar Cunha SI, Bocci M, Lövrot J, Eleftheriou N, Roswall P, Cordero E, et al. Endothelial ALK1 is a therapeutic target to block metastatic dissemination of breast cancer. Cancer Res. 2015;75:2445–56.Article CAS PubMed Google Scholar Liu C, Shi J, Li Q, Li Z, Lou C, Zhao Q, et al. STAT1-mediated inhibition of FOXM1 enhances gemcitabine sensitivity in pancreatic cancer. Clin Sci (Lond). 2019;133:645–63.Article CAS PubMed Google Scholar The Human Protein Atlas. 139567. Accessed 10 Feb 2021.TCGA Research Network. Accessed 10 Feb 2021.Emmink BL, Laoukili J, Kipp AP, Koster J, Govaert KM, Fatrai S, et al. GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer. Cancer Res. 2014;74:6717–30.Article CAS PubMed Google Scholar Zhang L, Zhou F, Drabsch Y, Gao R, Snaar-Jagalska BE, Mickanin C, et al. USP4 is regulated by Akt phosphoyla- tion and deubiquitylates TGF-beta type I receptor. Nat Cell Biol. 2012;14(7):717–26.Article CAS PubMed Google Scholar BDM-PUB. Accessed 6 May 2021.Sunamura N, Ohira T, Kataoka M, Inaoka D, Kugoh H. Regulation of functional KCNQ1OT1 lncRNA by β-catenin. Sci Rep. 2016;6(2):20690.Article CAS PubMed PubMed Central Google Scholar Starbase v.2.0. Accessed 26 Oct 2022.De Falco V, Napolitano S, Roselló S, Huerta M, Cervantes A, Ciardiello F, et al. How we treat metastatic colorectal cancer. ESMO Open. 2020;4:e000813.Article PubMed PubMed Central Google Scholar Li J, Qin S, Xu R, Yau TC, Ma B, Pan H, et al. Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncol. 2015;16:619–29.Article

TGF Do Something Archive - The Gear Forum

Effects on neurological and behavioral outcomes in acute ischemic stroke. Exp Ther Med 11(5):2015–2020. Article CAS PubMed PubMed Central Google Scholar Wang HM, Zhang T, Huang JK, Sun XJ (2013) 3-N-butylphthalide (NBP) attenuates the amyloid-β-induced inflammatory responses in cultured astrocytes via the nuclear factor-κB signaling pathway. Cell Physiol Biochem 32(1):235–242. Article CAS PubMed Google Scholar Wang F, Ma J, Han F, Guo X, Meng L, Sun Y, Jin C, Duan H, Li H, Peng Y (2016a) DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model. Sci Rep 6(1):19396. Article CAS PubMed PubMed Central Google Scholar Wang YG, Li Y, Wang CY, Ai JW, Dong XY, Huang HY, Feng ZY, Pan YM, Lin Y, Wang BX, Yao LL (2014) L-3-n-Butylphthalide protects rats’ cardiomyocytes from ischaemia/reperfusion-induced apoptosis by affecting the mitochondrial apoptosis pathway. Acta Physiol (Oxf) 210(3):524–533. Article CAS Google Scholar Tian X, He W, Yang R, Liu Y (2017) Dl-3-n-butylphthalide protects the heart against ischemic injury and H9c2 cardiomyoblasts against oxidative stress: involvement of mitochondrial function and biogenesis. J Biomed Sci 24(1):38. Article PubMed PubMed Central Google Scholar Yeh YH, Kuo CT, Chang GJ, Chen YH, Lai YJ, Cheng ML, Chen WJ (2015) Rosuvastatin suppresses atrial tachycardia-induced cellular remodeling via Akt/Nrf2/heme oxygenase-1 pathway. J Mol Cell Cardiol 82:84–92. Article CAS PubMed Google Scholar Severs NJ (2001) Gap junction remodeling and cardiac arrhythmogenesis: cause or coincidence? J Cell Mol Med 5(4):355–366. Article CAS PubMed Google Scholar Verheule S, Sato T, Everett T 4th et al (2004) Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res 94(11):1458–1465. Article CAS PubMed PubMed Central Google Scholar Swaney JS, Roth DM, Olson ER, Naugle JE, Meszaros JG, Insel PA (2005) Inhibition of cardiac myofibroblast formation and collagen synthesis. TGF is a Member at Bukkit Forums. Log in or Sign up. Bukkit Forums. Home Members TGF Last Activity: Joined: Messages: 113 Likes

TGF Do Something Challenge - The Gear Forum

Home Forums Topics For Phone/Device Forums (Click/Tap) 3D Printing Android Auto Android Mods Android TV Apps & Games Themes Wear OS Smartwatches Topics Windows 11 XDA Computing Artificial Intelligence AI & Machine Learning ML ****Contact Us Regarding Forum or Account Issues**** Devices Phone/Device Forums (Click/Tap) Asus News Asus Forums Google News Google Forums HTC News HTC Forums Honor News Honor Forums Huawei News Huawei Forums Lenovo News Lenovo Forums LG News LG Forums Motorola News Motorola Forums Nokia News Nokia Forums Nubia News Nubia Forums OnePlus News OnePlus Forums OPPO News OPPO Forums Razer News Razer Forums RealMe News RealMe Forums Samsung News Samsung Forums Sony News Sony Forums Vivo News Vivo Forums Xiaomi News Xiaomi Forums ZTE News ZTE Forums Guides What's new Log in Register New posts Manufacturers What's new New posts Latest activity Members Current visitors Menu Install the app Topics 3D Printing Android Auto Android Mods Android TV Apps & Games Themes Wear OS Smartwatches Windows 11 XDA Computing Terms and rules Privacy Security You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Launcher pro themes Thread starter ryan49er Start date Dec 13, 2010 Home Forums General Development Legacy & Low Activity Devices HTC Droid Eris Droid Eris Themes and Apps Breadcrumb Home Forums General Development Legacy & Low Activity Devices HTC Droid Eris Droid Eris Themes and Apps Prev 1 2 First Prev 2 of 2 Go to page Search